Exploring 3D Space

Dial-a-Molecule Theme 3 Synthesis College

Synthetic Tools for the Exploration of 3D Pharmaceutical Space


When: Friday 17th November 2017

Where: University of York


This free-to-attend meeting aims to bring together 80–100 researchers at all career stages, from industry and academia, to learn about and discuss recent developments in the synthesis, analysis and biological evaluation of 3D molecules and their pharmaceutical importance.

Planned aspects of the day include poster presentations (with prizes), breakout sessions designed to encourage networking, collaboration and improved industry/academic engagement, and research talks (ca. 30 minutes) from academic and industrial speakers.
Once signed up, delegates will be contacted in due course about the arrangements for the poster session (we anticipate that all delegates wishing to present a poster will be able to do so)


10.00–10.30 Registration, coffee.

Session 1: Chaired by Dr Will Unsworth (University of York)

10.30–11.00. Prof Joe Sweeney (University of Huddersfield) Title tbc

11.00–12.15. Industry/academia collaboration mini-session. Four short talks by academics who have established successful industry/academia collaborations connected to 3D pharmaceutical space. Followed by a 15 minute Q+A session for all speakers.

  • Prof Rob Stockman (University of Nottingham) Title tbc
  • Dr Liam Cox (University of Birmingham) Title tbc
  • Prof. Peter O’Brien (University of York) Title tbc
  • Prof. Nigel Simpkins (University of Birmingham)
    Challenges and Opportunities for 3D scaffold chemistry in pharmaceutical R&D

12.15–13.30. Lunch, including poster session. Exhibitions from Advion, Fluorochem and Radleys and a live demonstration of LLAMA (Dr James Firth, York).

Session 2: Chaired by Dr Paul Clarke (University of York)

  • 13.30–13.55 Dr Susannah Coote (Lancaster University)
    • Outside the box: Synthesis of new Cubane Dervatives
  • 13.55–14.20 Dr James Bull (Imperial College London)
    • Synthesis of N-Heterocycles as 3-D Fragments: Strategies for a Faster Escape from Flatland
  • 14.20–14.45 Dr Jeff St Denis (Astex)
    • Title tbc
  • 14.45–15.10 Dr Rob Young (GSK)
    • Why Pharma needs tools to explore 3D space; the pitfalls of flatness (and fatness)

15.10–15.45 Coffee/posters

Session 3: Chaired by Prof. Peter O’Brien (University of York)

  • 15.45–16.10 Dr Elaine O’Reilly (University of Nottingham)
    • Title tbc
  • 16.10–17.10 Prof Erick Carreira (ETH Zurich)
    • Title tbc

17.10 Drinks reception, then close.


ECRs may apply to Dial-a-Molecule for a bursary to attend.

Please register for the event here.