Kelly Kilpin

Author's posts

Descriptor-led Screening of NHC Ligands

C. Willans (University of Leeds), B. Nguyen (University of Leeds), N. Fey (University of Bristol) & S. Tyler (CatSci Ltd) As part of the support for the application of statistical methods to chemistry research, the network supported a new collaboration between early career researchers Dr Charlotte Willans and Dr Bao Nguyen (University of Leeds) with …

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Ligand-directed Selectivity in Copper-catalysed Allylic Amination

A. Malkov (Loughborough University) and N. Fey (University of Bristol) The Dial-a-Molecule network action on “Applying Statistical Methods to Chemistry Research” supported the establishment of a new collaboration between Prof. Andrei Malkov (AM) at Loughborough University, who leads a group of synthetic chemists, and Dr Natalie Fey (NF) at the University of Bristol, an expert …

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Staged Dataset for Design of Experiments (DoE)

P. Allan, A. Nordon and C. Jamieson, University of Strathclyde Understanding and optimising reactions is vital in the chemical and pharmaceutical industry to improve product quality and reproducibility. In addition it helps to minimise development costs, batch time and waste. Design of experiments (DoE) is a process used in many industrial and pharmaceutical applications to …

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Promoting the Education and Deployment of Statistical Methods in Academia

Introduction More and more, chemistry is taking advantage of the technological revolution that has taken place over the last 20 years.  For example, automation of what were once seen as manual procedures can now be routinely carried out 24/7 without the need for an operator to be present. As a consequence, increasingly large amounts of …

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Electrochemically Switchable Catalysts in Flow

Bao N. Nguyen, Charlotte E. Willans, Nik Kapur, (Institute of Process Research & Development, University of Leeds); Christopher Jones, (School of Biological and Chemical Sciences, Queen Mary University of London) Many important catalytic reactions happen through cycles of changes to the oxidation state of the metal catalyst to drive chemical conversion of starting materials to …

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Stabilised Bimetallic Metal Nanoparticles

Stabilised Bimetallic Metal Nanoparticles in Tailor-made Carbon Nanoreactors as Catalysts for Continuous-Flow Biomass Valorisation with Supercritical Fluids Dr. R. A. Bourne,a Dr. T. W. Chamberlain,a,b Dr. U. Hintermair,c & Dr. C. D. Smithd aSchool of Process, Environmental and Mechanical Engineering, University of Leeds, bSchool of Chemistry, University of Nottingham, cCentre for Sustainable Chemical Technologies, University of Bath, dSchool …

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Design and Additive Manufacturing for Flow Electrochemistry

PI: Steve Christie (Loughborough University), CoI; Russ Harris (Loughborough University), Ross Friel (Loughborough University), Roger Mortimer (Loughborough University) and Andy Wright (Andy Wright Ltd)   The 12 week project looked at designing and preparing an electrochemical flow cell by an additive manufacturing technique, ultrasonic consolidation. Elements of the proposal were successful: we could prepare the …

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Towards a National Academic Electronic Library

PI: Dr Simon J. Coles (University of Southampton), Co-I: Prof. Jeremy G. Frey (University of Southampton), Prof. Richard J. Whitby (University of Southampton), Dr Richard Kidd (Royal Society of Chemistry) & Dr Antony Williams (Royal Society of Chemistry)   Outputs relating to this PoC award include: ChemTrove: Enabling a Generic ELN to Support Chemistry through …

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Lead-Oriented Synthesis: Exploring Drug-Relevant Chemical Diversity – Meeting Report

GSK Stevenage, 25 September 2015 Lead-Oriented Synthesis: Exploring Drug-Relevant Chemical Diversity was a one-day meeting organized by the Dial-a-Molecule Grand Challenge Network, and held at GlaxoSmithKline’s Stevenage site on September 25, 2015. The meeting attracted 92 registered delegates, and featured scientific talks from academic and industrial leaders in the field. It also coincided with the …

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Enabling Data Driven Chemistry

Dial-a-Molecule Grand Challenge Institute Rapid reaction analysis has been identified by the Dial-a-Molecule Grand Challenge as an area most in need of a central facility, due to the cost of equipment/instruments, and even more critically, the provision of expertise to provide training in the use and interpretation of data. Such a facility would give access to state-of-the-art …

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