Select publications
Lopez DM, Maltby CJ, Warming H, Divecha N, Vargas-Caballero M, Coldwell MJ, Deinhardt K: A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau. Front. Neurosci., Insights into Neurodegeneration 2023 Vol. 17
Maltby CJ, Schofield JPR, Houghton SD, O’Kelly I, Vargas-Caballero M, Deinhardt K, Coldwell MJ: A 5’ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation. Nucleic Acids Res, Sep 25; 48(17): 9822-9839
Baksh PE, Ostrčil M, Miszczak M, Pooley C, Chapman RT, Wyatt AS, Springate E, Chad JE, Deinhardt K, Frey JG, Brocklesby WS: Quantitative & Correlative Extreme Ultraviolet Coherent Imaging of Mouse Hippocampal Neurons at High Resolution. Sci. Adv, 01 May 2020: Vol. 6, no. 18, eaaz3025 Highlighted in EurekAlert, NOVUS light
Deinhardt K: A receptor that lets dementia-associated tau proteins into neurons. Nature 2020, 580:326-7
Hallinan GI, Vargas-Caballero M, West J, Deinhardt K: Tau misfolding efficiently propagates between individual intact hippocampal neurons. Highlighted in Neuronline; detailed protocol at 10.21769/BioProtoc.3718
Warming H, Pegasiou CM, Pitera AP, Kariis H, Houghton SD, Kurbatskaya K, Ahmed A, Grundy P, Vajramani V, Bulters D, Altafaj X, Deinhardt K, Vargas-Caballero M: A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain. Mol Brain. 2019 Jul 4;12(1):64
Pitera AP, Asuni AA, O’Connor V and Deinhardt K: Pathogenic tau does not drive activation of the unfolded protein response. J. Biol. Chem. 2019 Jun 21;294(25):9679-9688
Holloway PM, Hallinan GI, Hegde M, Lane SRI, Deinhardt K, West J: Asymmetric confinement for defining outgrowth directionality. Lab Chip, 2019, 19, 1484 – 1489
Bowling H, Zhang G, Bhattacharya A, Pérez-Cuesta LM, Deinhardt K, Hoeffer CA, Neubert TA, Gan WB, Klann E, Chao MV: Antipsychotics Activate mTORC1-Dependent Translation to Enhance Neuronal Morphological Complexity. Sci Signal. 2014 Jan 14;7(308):ra4
Highlighted in Science Signaling Podcast
Anastasia A, Deinhardt K, Chao MV, Will NE, Irmady K, Lee FS, Hempstead BL, Bracken C: The Val66Met Polymorphism Alters the BDNF Prodomain Structure to Induce Neuronal Growth Cone Retraction. Nat. Commun 2013 (4): article 2490
Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL: Neuronal growth cone retraction relies upon proneurotrophin receptor signaling through Rac. Sci. Signal. 2011 Dec;4(202) ra82 Highlighted in Editors’ Choice, Science
Jeanneteau F*, Deinhardt K*, Miyoshi G, Bennett AM, Chao MV: The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching. Nat. Neurosci. 2010 Nov;13(11):1373-9. Highlighted in Faculty of 1000 Biology
Deinhardt K, Reversi A, Berninghausen O, Hopkins C, Schiavo G: Neurotrophins redirect p75NTR from a clathrin-independent to a clathrin-dependent pathway coupled to axonal transport. Traffic 2007 8(12): 1736-1749
Deinhardt K*, Salinas S*, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C, Schiavo G: Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron 2006 52(2): 293-305. Highlighted in Faculty of 1000 Biology
Deinhardt K*, Berninghausen O*, Hopkins C, Schiavo G: Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol. 2006 174: 459-471