Select publications
Maltby CJ, Schofield JPR, Houghton SD, O’Kelly I, Vargas-Caballero M, Deinhardt K, Coldwell MJ: A 5’ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation. Nucleic Acids Res, Sep 25; 48(17): 9822-9839
Baksh PE, Ostrčil M, Miszczak M, Pooley C, Chapman RT, Wyatt AS, Springate E, Chad JE, Deinhardt K, Frey JG, Brocklesby WS: Quantitative & Correlative Extreme Ultraviolet Coherent Imaging of Mouse Hippocampal Neurons at High Resolution. Sci. Adv, 01 May 2020: Vol. 6, no. 18, eaaz3025 Highlighted in EurekAlert, NOVUS light
Deinhardt K: A receptor that lets dementia-associated tau proteins into neurons. Nature 2020, 580:326-7
Hallinan GI, Vargas-Caballero M, West J, Deinhardt K: Tau misfolding efficiently propagates between individual intact hippocampal neurons. Highlighted in Neuronline; detailed protocol at 10.21769/BioProtoc.3718
Warming H, Pegasiou CM, Pitera AP, Kariis H, Houghton SD, Kurbatskaya K, Ahmed A, Grundy P, Vajramani V, Bulters D, Altafaj X, Deinhardt K, Vargas-Caballero M: A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain. Mol Brain. 2019 Jul 4;12(1):64
Pitera AP, Asuni AA, O’Connor V and Deinhardt K: Pathogenic tau does not drive activation of the unfolded protein response. J. Biol. Chem. 2019 Jun 21;294(25):9679-9688
Holloway PM, Hallinan GI, Hegde M, Lane SRI, Deinhardt K, West J: Asymmetric confinement for defining outgrowth directionality. Lab Chip, 2019, 19, 1484 – 1489
Bowling H, Zhang G, Bhattacharya A, Pérez-Cuesta LM, Deinhardt K, Hoeffer CA, Neubert TA, Gan WB, Klann E, Chao MV: Antipsychotics Activate mTORC1-Dependent Translation to Enhance Neuronal Morphological Complexity. Sci Signal. 2014 Jan 14;7(308):ra4
Highlighted in Science Signaling Podcast
Anastasia A, Deinhardt K, Chao MV, Will NE, Irmady K, Lee FS, Hempstead BL, Bracken C: The Val66Met Polymorphism Alters the BDNF Prodomain Structure to Induce Neuronal Growth Cone Retraction. Nat. Commun 2013 (4): article 2490
Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL: Neuronal growth cone retraction relies upon proneurotrophin receptor signaling through Rac. Sci. Signal. 2011 Dec;4(202) ra82 Highlighted in Editors’ Choice, Science
Jeanneteau F*, Deinhardt K*, Miyoshi G, Bennett AM, Chao MV: The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching. Nat. Neurosci. 2010 Nov;13(11):1373-9. Highlighted in Faculty of 1000 Biology
Deinhardt K, Reversi A, Berninghausen O, Hopkins C, Schiavo G: Neurotrophins redirect p75NTR from a clathrin-independent to a clathrin-dependent pathway coupled to axonal transport. Traffic 2007 8(12): 1736-1749
Deinhardt K*, Salinas S*, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C, Schiavo G: Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron 2006 52(2): 293-305. Highlighted in Faculty of 1000 Biology
Deinhardt K*, Berninghausen O*, Hopkins C, Schiavo G: Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol. 2006 174: 459-471