The University of Southampton

Engineering Replacement Body Parts 2023

UOSM2031

Stem cells and Neurodegeneration(Practice)

Should We Cross the Great Moral Divide? Maybe”

-Someone

Regenerative stem cell theory!!!

The brain is complex environment made of bundle of connections signalling and communicating with one another; when one of said connections is interrupted problems occur that can affect the entire body.

Parkinson’s is a neurodegenerative disease of the central nervous system, and pluripotent stem cells have been found to minimise it symptoms by replacing the dopamineregic neurons affected.

Confliction at Uni

Are you going club tonight?

Everyone at university

Battling between what to do during the week is a immense confliction for me.

  • Tennis
  • Basketball
  • Education
  • Clubbing
  • Going pub
  • Eating out
  • Making dinner

All these aspects provide me with constant stress and anxiety. Things like making food requires tremendous effort but unfortunately it has to be done. Same applies to other chores such as going shopping which feels like an entire day trip out. By the time im back from the shops I feel accomplished for the day and despite it being 11am, i feel like I can watch Netflix for the remainder of the day and fell guilt free doing so. The only issue with this, is now Im now 20 lectures behind and i would catch up tomorrow… but its society night today so ill be paralytic tomorrow from a few too many of them horrible jesticles. Don’t worry though, ill recover just in time for trilogy Thursdays.

If your find out why everyone goes jesters on a wednesday night because im still trying to understand. When i went last time i had grown a whole ecosystem of mould on my new shoes. That taught me a lesson that university could never. I completely agree with this articles position on jesters…

The UK’s 10 Worst Nightclubs | Student Blog UK | AFS (accommodationforstudents.com)

Im not sure this photo is from jesters but… i wouldnt be surprised. In fact it looks slighly to well maintained to be jesters.

These are the type of videos i encourage everyone in my situation to watch. Its a new semester and well im currently here at my 9am tutorial so im doing better than last semester already.

Welcome to UoSM Engineering Replacement Body Parts

HI EVERYONE!

My name is Sofia and I am a second-year student of Biomedical Sciences.

I have decided to enrol in this module because I am particularly interested in prosthesis but also other relevant applications of new technologies in medical settings.

I hope I will make new friends who will enjoy the module as much as me. If you need any help, do not hesitate to keep in touch!

Sofia

Girl sees herself with a “normal-looking” ear for the first time

I have recently watched this video about a prosthetic ear that was implanted on a girl with a disease called “Microtia”, which basically completely deforms the shape and hearing abilities of the patient. Her first reaction while seeing herself for the first time with a new “normal-looking” ear is thrilling. This video reminds me the huge power that engineering has to completely revolutionise people’s lives.

BUCS- what’s the fuss about?

BUCS: British universities and college sport

If you’re involved in BUCS you’ll know it takes over your every Wednesday. Train twice week. Lose. Drown your sorrows at the social. Repeat.

What makes it worth it? The people you meet and the friends you make along the way.

BUCS history

Founded in 1918, with the first athletics meet taking place only a year later. In 1922, new sports were introduced such as, football, hockey and swimming. Until 2008, BUCS was not unified under one governing body. It consisted of the UCS (University and college sport) and the BUSA (British University sport association) which became BUCS on the 31st of October 2008.

My sport- Netball

Building Skills for Beyond Education

As a third-year natural sciences student here at Southampton, I am assessed in a variety of ways, including essays, scientific reports and presentations. However, being assessed in this way is new to me, and it is one of the things that is exciting me about this module. Another key part of my degree is the focus on interdisciplinary learning across a wide range of modules, which this module will allow me to develop. The content covered in this module is all new to me and looks incredibly interesting, especially the content on prostheses and stem cell ethics. As well as just being interesting, I believe that discussions about the ethics of stem cells in research are crucial in preparing the next generation for leaps and bounds in scientific discovery.

Within the Natural Sciences degree programme you get a large amount of choice, and I mainly focus on organic chemistry and some aspects of biology, including immunotherapy. I also have compulsory NATS modules which I always enjoy, which are accessible to all of us despite all being from different scientific backgrounds. One that particularly resonated with me was about climate chemistry, and was assessed by individual presentations about a chosen topic. The topic I chose was about the impact of shipping on the air quality in port cities, and this is now the basis for my third year project which I am currently working on. The NATS modules are assessed in a way that builds skills outside of written essays and timed examinations, which I believe is really important in preparing us for a life outside of education. This Engineering Replacement Body Parts will build on these skills, including giving presentations, working within a team and expanding knowledge beyond the lecture content.

The stem cell debate is ongoing
An introduction to stem cells and their uses

Introduction

Coming from a physics background, this module was something completely new and different for me. Where I’m used to everything from blackholes to quantum wave functions, this module is a way to step outside my comfort zone and explore how physics and engineering can be applied to help people. One way that physics and biomed appear to overlap (from my limited research) is in the world of nanomedicine. Defined as ‘a branch of medicine that applies the knowledge and tools of nanotechnology to the prevention and treatment of disease.’ nanomedicine seems like it may be future of targeted drug delivery. Utilizing things within the nano dimensions such as sensors and robots it can be used for delivery and sensing purposes of live cells, nanomedicine may in future provide a cleaner, safer and more accurate future for internal medicine.

Introduction

The concepts and assessment methods in this module are very different from my degree course which is Physics. Last semester I studied nano-physics this really interested me. I thought it would be interesting to get the chance to explore other disciplines than pure physics as many of the limitations of nano and micro physics are only apparent when looking through the lens of another subject, like many imaging techniques being destructive due to high energies required or needing thin or conducting substrates or very low temperatures due to thermal noise.

Engineering Replacement Body Parts

Hello, my name is Evan Masters, I’m 19 years old and am in my second year of Biomedical science. In what little spare time I have I enjoy running, gaming, gym and procrastinating. In terms of societies, I’m a bit lazy, though I do play esports for Southampton University and am playing in the qualifiers for a £10000 tournament tonight (02/02/2023), so wish me luck.

Me (Pictured left) and Professional Rocket league player Kyle torment Storer (Pictured right), he may be a millionaire from videogames, but I’m taller.

Why did I choose this module? First and foremost, this actually looks fun and interesting, especially when my other option was Protein Structure and Function. This also is mostly assessed by coursework which really helps with the stress of exam period. I also might be able to understand some amount of the module, unlike Protein Structure and Function, I really didn’t want to do that module.

I find stem cell research really interesting, initially I was going to do an integrated masters with placement in Scotland in stem cell Embryonics, but alas I did not have a chemistry A level which was required. My brother is also missing a lung so growing him a new one would give me irreputable leverage over him and strengthening my position as favourite child.

Other than that, I tend to enjoy learning outside my field so doing an interdisciplinary module, especially one involving engineering aspects, should be an enjoyable time :).

Introduction

I’m Florrie, I am an exchange student from New Zealand. My university in NZ is called Victoria University of Wellington. I am doing a whole year here in Southampton. I study Biomedical Science and am in my final year. Although I live in NZ I am originally from the UK, I moved to NZ when I was 5 years old. I have also lived in Sydney, Australia. I live in Wellington, which is the capital city. New Zealand is a beautiful country, it has a similar land mass to UK but only has a population of 5 million. One of the coolest things about New Zealand is that we have serval active volcanoes. I have attached a video below of things to do in New Zealand.

The topic I am most excited about in this module is stem cells and research ethics. I am looking forward to learning about how stem cells can be used to help cure diseases and aid in medicine. It will be interesting to learn about how ethics affect the work that can be done and how they are used in regulating research. I have done some lab work with Henrietta lacks cells back at my uni at home which was really interesting seeing how they develop depending on what chemical they are exposed to. It was also comparing the growth of cancerous stem cells to normal ones.

Henrietta Lacks Cells

Lego- building blocks for life?

This is David Aguilar, he was born with Poland Syndrome which is a condition that affects the chest muscles, causing them to under develop at birth. Blockage of blood vessels in the womb can lead to this and other conditions such as Brachydactyly.

David Aguilar with his Lego prosthetic arm.

David had an interest as a child for Lego which lead to his development of his prosthetic arm. He used Lego Technic to create his model the ‘MK-1’ (iron man reference) which involved motors and his adaptation of fine motor movement with fingers and pressure sensors.

David is still evolving his prosthesis and creating new updated models using cables to contract to simulate muscle contraction. There is a book, documentary and many more articles about Davids story, including his youtube ‘Hand Solo’.

This video explains more about Davids story from himself

As a Lego employee myself it is amazing to see the extent to which Lego can go and not only be a bit of fun for kids. It is amazing how life changing it really is and the possibilities there are with it.

I believe Lego technic could be explored more in the world of prosthesis not only for function but to help introduce the topics to children to allow them to explore the world of STEM and possibly aid children who have conditions where prosthesis are an option, Lego may make this seem less daunting and allow them to explore this whilst having fun.

Ria Hill