The University of Southampton

George Best- at his worst

GEORGE BEST- at his worst

Combing my piqued interest in ethical values from the lectures and my love for sports, upon learning about ‘organ harvesting’ and the Alder Hey case study, which looked at the use of organs in consensual ways, my mind instantly went to the case study of George Best. A world renound football player who wasted his donated liver on an alcohol addition he struggled with for over 40 years.

The three images display George Best throughout his life

Back to basics

Organ transplantation is no light conversation- especially when it comes to who is ‘deserving’. The NHS have a highly strategised offering system and the average wait time for a liver in the UK is 3-4 months. Which is exceptional considering the average person can live with liver cirrhosis for an average of 12 years. More information on the causes of liver cirrhosis can be found here.

Under the NHS, there is no requirement to stop drinking before a liver transplant- even if the liver failure is alcohol induced. This to me, is absurd. The NHS should aim to fix the problem at its origin- not waste valuable resources.

How would you feel, knowing that your loved ones liver went to someone who drank themselves back into the situation that brought them to the operating table in the first place?

More on George

George Best was one the first of his kind- the first true football ‘superstar’ in the 1960’s. However, by the 70’s the first glimpses of the alcoholism that would consume him for the rest of his life. By 2000, George Best had been diagnosed with severe alcohol induced liver damage. In 2002, Best received a new liver at public expenses (on the NHS), which received huge controversy. Less than a year later, Best was spotted openly drinking. Three years later he started drinking again and died soon after.

A short documentary commentating on the final years of George Best and his struggle with alcohol

Fair vs Right

Looking from different perspectives:

Liberation: Seeks to maximise freedom and the individuals rights. Therefore, the choice is the patients alone.

Paternalistic: Aims to chose a course of action in the patients best interest, but without the patients consent. For example, required rehabilitation prior to the organ transplant.

Utilitarian: Focuses on optimal outcomes via right or wrong. Requires the outcome that produces the greatest good for the greatest number. In this case, going ahead with the organ transplant would save a life and therefore have the greatest benefit.

Taking an ethical stance, I believe it is always right to treat those in need. No matter the cause of illness of injury. Saving lives and enabling a more enjoyable life are the priority. However, I do not believe it is fair to treat those incapable of maintaining their new functioning organ, as described with George Best. If those facing psychological difficulties are unable to receive a liver transplant, is it right we provide for those incapable of staying off the booze?

Moving forward?

I found researching this case incredibly insightful. George Best is not the first person to raise such an ethical dilemma, and he certainly wont be the last. In fact, those who require liver transplants in the future will only rise due to the impacts of COVID-19 and the increased alcohol consumption it has brought. My hope is that the increasing numbers of those suffering with alcoholism will force health care organisations globally to take longer-lasting action, such as, putting measures in place to combat the individuals struggle with alcohol before operating.

Twins always win

ERIN LOVELY

TWINS ALWAYS WIN

Sourcing cells can come for four different origins: a human donor (allogenic cells), a donor from oneself (autogenic cells), from an animal (xenogeneic cells), and from an identical twin (syngeneic cells).

Unfortunately, under 0.3% of the population have the luxury of obtaining syngeneic cells. Not only do you have to be born a twin, fight for survival against your sibling in the womb and survive the inevitable premature birth (well, a 50-60% chance) – you have to be identical. However, if you are lucky enough to be within the 0.3%, here are some of the benefits: Syngeneic stem cell transplants are the simplest source of stem cells available at present. The Syngeneic transplant offers little risk of rejection and the immune system rapidly recovers. Almost half of organ transplants between twins require no immunosuppressant drugs.

How far can the use of Syngeneic cells go? … so far extensive proof of successful uses of bone marrow/stem cell transplants and organ transplants can be found.

(Examples of successes in surgery due to the patients being twins below.)

EXAMPLES OF SUCESS

KIDNEY TRANSPLANTS

The Herrick Twins
23rd of December, 1954, Murray performing the first ever successful human organ transplant
The first successful kidney transplant

The story of the first successful human organ transplant took place between identical twins (top left). Extensive tests were carried out on the twins to ensure the success of the operation. However, the risks of the procedure were not the only issue faced by surgeon, Joseph Murray. Murray described the ethical dilemma they faced, in acquiring the kidney from a healthy person. Ronald Herrick (donor) risked his life, for no benefit of his own, except saving his beloved brother, Richard (patient).

EXAMPLES OF SUCCESS

OVARY TRANSPLANT

Ovary transplant from identical twin reverses early menopause and results in successful birth. Three months after the ovary transplant the twin sister gained her period back after 10 years, and three months after that, she fell pregnant. The conception and birth of the baby were completely natural.

Illustration of ovary from ovarian transplant

Many identical twins have now received ovary transplants. All the successful transplants aid in the conclusion that ovarian transplants restore ovary function completely.

TWINS ALWAYS WIN

CONCLUSIONS

Its impossible to imagine a world where everyone has an identical twin, but, just for a second, lets imagine we do… How many problems it would solve; no waitlists for organ transplant, more reliable infertility solutions, more readily available stem cells from bone marrow and, all ethical issues pushed to the side in the name of love.

How do we bridge the gap between organ transplant sucess rate in identical twins and everyone else ? I think an advancement in immunosuppressant drugs would help bridge to gap between identical twins and everyone else. If there was a more effective immunosuppressant drug available to those under going organ transplants, the success rate would increase and the risk would decrease.

Hopefully in the future we will have scientific advancements that achieve this, but for now, its better to be a twin.

BUCS- what’s the fuss about?

BUCS: British universities and college sport

If you’re involved in BUCS you’ll know it takes over your every Wednesday. Train twice week. Lose. Drown your sorrows at the social. Repeat.

What makes it worth it? The people you meet and the friends you make along the way.

BUCS history

Founded in 1918, with the first athletics meet taking place only a year later. In 1922, new sports were introduced such as, football, hockey and swimming. Until 2008, BUCS was not unified under one governing body. It consisted of the UCS (University and college sport) and the BUSA (British University sport association) which became BUCS on the 31st of October 2008.

My sport- Netball