{"id":173,"date":"2017-06-08T10:03:54","date_gmt":"2017-06-08T10:03:54","guid":{"rendered":"http:\/\/www.efolio.soton.ac.uk\/blog\/discoverneuroscience\/?page_id=173"},"modified":"2019-06-08T13:03:12","modified_gmt":"2019-06-08T12:03:12","slug":"practical-experience","status":"publish","type":"page","link":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/for-teachers\/teaching-resources\/practical-experience\/","title":{"rendered":"Research Projects\/Practicals with Curriculum Links"},"content":{"rendered":"<p><span style=\"font-family: verdana, geneva, sans-serif\">The University has support in place for 4 different areas of <span class='tooltipsall tooltipsincontent classtoolTips8'>Neuroscience<\/span> which sixth form students could undertake practicals or research projects in. Click on the links below for more information on each of the areas;<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-180 size-medium alignleft\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/c.elegans-e1496918121658-300x224.png\" alt=\"\" width=\"300\" height=\"224\" \/><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><strong><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Worm.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Worms:<\/a><\/strong><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><em><span class='tooltipsall tooltipsincontent classtoolTips11'>C. elegans<\/span><\/em> \u2013 a tiny roundworm that you can keep on a petri dish, breed, expose to different chemicals (e.g. alcohol).<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">If you are interested in the effects of drugs, animal behaviour or genetics, this may work for you.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><strong><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Eye.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Eyes:<\/a><a class=\"CID9a87ceec-50e9-4d03-b0c7-994c734bcf1e\">\u00a0<\/a><a class=\"CID9a87ceec-50e9-4d03-b0c7-994c734bcf1e\">\u00a0<\/a><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-181 size-medium alignleft\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/eyes-e1496918183365-300x226.png\" alt=\"\" width=\"300\" height=\"226\" \/><\/strong><strong>\u00a0\u00a0<\/strong><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">There are techniques for looking at the whole <span class='tooltipsall tooltipsincontent classtoolTips21'>Retina<\/span>, sections through it, 3D images, different species, staining sections with special fluorescent probes, etc..<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Do the retinas of different species have different structures? Can we model an eye disease by adding things to isolated retinas? Do different retinas have different numbers of cells, at different points?<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-182 size-medium alignleft\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Fly-e1496918252747-300x233.png\" alt=\"\" width=\"300\" height=\"233\" \/><\/span><\/p>\n<p style=\"text-align: left\"><span style=\"font-family: verdana, geneva, sans-serif\"><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Flies.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Flies:<\/strong><\/a><\/span><\/p>\n<p style=\"text-align: left\"><span style=\"font-family: verdana, geneva, sans-serif\"><span class='tooltipsall tooltipsincontent classtoolTips12'>Drosophila<\/span> melanogaster (a tiny fruit fly)<\/span><\/p>\n<p style=\"text-align: left\"><span style=\"font-family: verdana, geneva, sans-serif\">Transfer them to a measuring cylinder and use your phone to record them climbing up \u2013 a simple \u2018climbing assay\u2019.<\/span><\/p>\n<p style=\"text-align: left\"><span style=\"font-family: verdana, geneva, sans-serif\">They will get slower as they age, but is this affected by sex, how much sleep they get, drugs, vitamins?<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><strong><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Rod-and-Frame.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Rod and Frame:<\/a><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-183 size-medium alignleft\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Rod-and-Frame-269x300.png\" alt=\"\" width=\"269\" height=\"300\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Rod-and-Frame-269x300.png 269w, https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Rod-and-Frame.png 338w\" sizes=\"auto, (max-width: 269px) 100vw, 269px\" \/><\/strong><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">The rod and frame illusion \u2013 a computer programme where people have to rotate a line until they think it is perfectly vertical. Interestingly,<\/span><span style=\"font-family: verdana, geneva, sans-serif\">\u00a0you can distract people by putting in a background that is skewed.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Does the ability to \u2018set the line\u2019 vary with age, sex, sporting ability, how much coffee you drink, time of day, handedness?<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/EEG-and-GSR-practical.doc\"><span style=\"text-decoration: underline\"><strong><span class='tooltipsall tooltipsincontent classtoolTips1'>EEG<\/span> and <span class='tooltipsall tooltipsincontent classtoolTips0'>GSR<\/span> used to Investigate Intact Nervous System Functioning:<\/strong><\/span><\/a><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Investigate electric potentials that can be recorded from the surface of the skin to give information about the functioning of the intact nervous system.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Looking at how the electroencephalogram records activity in the brain.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Understanding how skin potential response reflects activity in the autonomic nervous system.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\"><a href=\"http:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-content\/uploads\/sites\/329\/2017\/06\/Yr-10-Lie-Detector-2013.doc\"><span style=\"text-decoration: underline\"><strong><span class='tooltipsall tooltipsincontent classtoolTips4'>ECG<\/span> and <span class='tooltipsall tooltipsincontent classtoolTips5'>EOG<\/span> used for the Recording of Surface Potentials<\/strong><strong>:<\/strong><\/span><\/a><\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">Students will investigate two types of potentials that can be recorded from the surface of the skin and can give information about the functioning of the intact nervous system.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">The <span class='tooltipsall tooltipsincontent classtoolTips5'>Electrooculogram<\/span> records potential changes associated with eye movements and can be used to detect changes in the direction of gaze.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif\">The skin potential response reflects activity in the autonomic nervous system supplying the sweat glands, and can be used to detect responses to sensory and emotional stimuli.<\/span><\/p>\n<script type=\"text\/javascript\"> toolTips('.classtoolTips0','A change in the electrical resistance of the skin caused by emotional stress, measurable with a sensitive galvanometer, e.g. in lie-detector tests.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips1','<span style=\"font-family: verdana, geneva, sans-serif\">The measurement of electrical activity in different parts of the brain and its recording as a visual trace (on paper or on an oscilloscope screen).<\/span>'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips3','The part of the nervous system responsible for control of the bodily functions not consciously directed, such as breathing, the heartbeat, and digestive processes.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips4','A record or display of a person\\'s heartbeat produced by electrocardiography.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips5','A record of the standing voltage between the front and back of the eye that is correlated with eyeball movement (as in REM sleep) and obtained by electrodes suitably placed on the skin near the eye.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips5','A record of the standing voltage between the front and back of the eye that is correlated with eyeball movement (as in REM sleep) and obtained by electrodes suitably placed on the skin near the eye.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips8','Any or all of the sciences, such as neurochemistry and experimental psychology, which deal with the structure or function of the nervous system and brain.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips11','<span style=\"font-family: verdana, geneva, sans-serif\">Also known as roundworm, this is a free-living, transparent <span class='tooltipsall tooltipsincontent classtoolTips18'>Nematode<\/span>, about 1 mm in length, that lives in temperate soil environments.<\/span>'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips12','A small fruit fly, used extensively in genetic research because of its large chromosomes, numerous varieties, and rapid rate of reproduction.'); <\/script><script type=\"text\/javascript\"> toolTips('.classtoolTips21','<span style=\"font-family: verdana, geneva, sans-serif\">A layer at the back of the eyeball that contains cells sensitive to light, which trigger nerve impulses that pass via the optic nerve to the brain, where a visual image is formed.<\/span>'); <\/script>","protected":false},"excerpt":{"rendered":"<p>The University has support in place for 4 different areas of Neuroscience which sixth form students could undertake practicals or research projects in. Click on the links below for more information on each of the areas; Worms: C. elegans \u2013 a tiny roundworm that you can keep on a petri &hellip;<\/p>\n","protected":false},"author":3738,"featured_media":0,"parent":49,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-173","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/pages\/173","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/users\/3738"}],"replies":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/comments?post=173"}],"version-history":[{"count":2,"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/pages\/173\/revisions"}],"predecessor-version":[{"id":1205,"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/pages\/173\/revisions\/1205"}],"up":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/pages\/49"}],"wp:attachment":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/discoverneuroscience\/wp-json\/wp\/v2\/media?parent=173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}