When<\/strong>: 29th November 2018, 10.00-17.00.<\/p>\n Where<\/strong>: GSK, Stevenage.<\/p>\n Overview: <\/strong>Scale-up of complex organic and bio-catalytic processes remains a significant challenge due to low observability of state variables and, frequently, absence of mechanistic models of the reactions. A raft of new tools is emerging in this topic, relating to increased observability (new sensor methods), development of \u2018good-enough\u2019 black box models based on machine learning approaches, new kinetic methods, new methods in design of experiments and development of process models, as well as the increased understanding in physical organic chemistry and computer-aided molecular design.<\/p>\n This event is aimed at practitioners in the field, industrial and academic method developers as a networking and research agenda-setting event: what is the state-of-the-art, what research challenges are emerging as a result of developments in the neighbouring fields (robotics, AI, machine learning, systems biology, synthetic biology, high throughput analytics, novel business models for manufacturing, new feedstocks, etc), where is progress required? The event will result in a white-paper and should stimulate future research proposals and collaborative research projects.<\/p>\n Registration for the event is open here<\/a>.<\/p>\n Scientific and organising committee: Richard Bourne (Leeds), Alexei Lapkin (Cambridge), Federico Galvanin (UCL), Robin Attrill (GSK).<\/p>\n Draft Programme<\/strong><\/p>\n 10:00 arrival, registration, tea\/coffee<\/p>\n 10:30 Introduction<\/p>\n Theme 1: Molecular modelling for process design<\/strong><\/p>\n 10:45-11:15 \u2018Computer-aided molecular design\u2019. Tbc<\/p>\n 11:15-11:45 \u2018From Molecules to Reactors: Methods, Applications and Opportunities for Catalytic Process Design\u2019 – Dr Michail Stamatakis, UCL<\/p>\n 11:45-12:15 \u2018Development and application of numerical simulation and optimization techniques for improved design and operation of complex reaction systems\u2019 – Dr Federico Galvanin, UCL<\/p>\n <\/p>\n 12:30-13:30 Lunch, Networking<\/strong><\/p>\n <\/p>\n Theme 2: Tools and methodologies<\/strong><\/p>\n 13:30-14:00 \u2018Rapid Development of Processes using Automated Flow Reactors and Machine Learning Algorithms\u2019 -Dr Richard Bourne, University of Leeds<\/p>\n 14:00-14:30 \u2018A systematic function-based approach to optimal reactor and process design\u2019- Prof. Hannsj\u00f6rgFreund, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg<\/p>\n 14:30-15:00 \u2018Evaluating the Robustness of Industrial Scale Bioprocesses: Combining PAT and Scale-Down Bioreactors\u2019<\/span>Prof. Peter Neubauer, Technische Universit\u00e4t Berlin.<\/p>\n 15:00-15:30 Coffee break<\/p>\n Theme 3: Implementation. Automation and scaling. Continuous processes. Mixed batch-continuous.<\/strong><\/p>\n 15:30-16:00 \u2018Application of process simulation for continuous processing\u2019 –<\/span>Flavien Susanne, GSK<\/p>\n 16:00-16:30 \u2018DynoChem prediction and simulation in process design and scale-up\u2019 – Drs Colm Cotter and Lucie Miller Potucka, AstraZeneca<\/span><\/p>\n 16:30 Facilitated summary discussion<\/p>\n 17:00 Close of meeting<\/p>\n <\/p>\n <\/p>\n We thank our Sponsors:<\/p>\n Scale-up Systems (Dynochem)<\/a><\/p>\n TeledyneIsco<\/a><\/p>\n <\/a>![\"\"](\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2018\/04\/Signage-2.jpg?resize=1140%2C165\")
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