{"id":3530,"date":"2017-07-04T15:25:08","date_gmt":"2017-07-04T14:25:08","guid":{"rendered":"http:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/?page_id=3530"},"modified":"2018-04-10T13:47:08","modified_gmt":"2018-04-10T12:47:08","slug":"3d_space","status":"publish","type":"page","link":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/3d_space\/","title":{"rendered":"Exploring 3D Space"},"content":{"rendered":"<p><span style=\"font-size: 16pt\"><strong>Dial-a-Molecule Theme 3 Synthesis College<\/strong><\/span><\/p>\n<p><span style=\"font-size: 18pt;color: #0000ff\"><strong>Synthetic Tools for the Exploration of 3D Pharmaceutical Space<\/strong> <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>When<\/strong>:\u00a0Friday 17th November 2017<\/p>\n<p><strong>Where<\/strong>:\u00a0University of York<\/p>\n<p><strong>Overview:<\/strong><\/p>\n<p>This free-to-attend meeting brought together 80 researchers at all career stages, from industry and academia, to learn about and discuss recent developments in the synthesis, analysis and biological evaluation of 3D molecules and their pharmaceutical importance.<\/p>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p><strong>The program of talks and activities comprised:<\/strong><\/p>\n<\/div>\n<\/div>\n<div class=\"section\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p><strong>Session 1:<\/strong> Chaired by Dr Will Unsworth (University of York)<\/p>\n<p>10.30\u201311.00. Prof Joe Sweeney (University of Huddersfield) Title tbc<\/p>\n<p>11.00\u201312.15. Industry\/academia collaboration mini-session. Four short talks by academics who have established successful industry\/academia collaborations connected to 3D pharmaceutical space. Followed by a 15 minute Q+A session for all speakers.<\/p>\n<ul>\n<li>Prof Rob Stockman (University of Nottingham).\n<ul>\n<li>European Lead Factory \u2013 an Industry\/academic Partnership in Drug Discovery\n<div class=\"page\" title=\"Page 1\"><\/div>\n<\/li>\n<\/ul>\n<\/li>\n<li>Dr Liam Cox (University of Birmingham).\n<ul>\n<li>Innovative Training Network European Industrial Doctorate Training Programmes: EU Funding Opportunities post Brexit?\n<div class=\"page\" title=\"Page 1\"><\/div>\n<\/li>\n<\/ul>\n<\/li>\n<li>Prof. Peter O\u2019Brien (University of York).\n<ul>\n<li>Fragment-Based Drug Discovery in 3-D: Academia meets Industry.<\/li>\n<\/ul>\n<\/li>\n<li>Prof. Nigel Simpkins (University of Birmingham).\n<ul>\n<li>Challenges and Opportunities for 3D scaffold chemistry in pharmaceutical R&amp;D<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>12.15\u201313.30. Lunch, including poster session. Exhibitions from Advion, Fluorochem and Radleys and a live demonstration of LLAMA (Dr James Firth, York).<\/p>\n<p><strong>Session 2:<\/strong> Chaired by Dr Paul Clarke (University of York)<\/p>\n<\/div>\n<\/div>\n<div class=\"section\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<ul>\n<li>13.30\u201313.55 Dr Susannah Coote (Lancaster University)\n<ul>\n<li>Outside the box: Synthesis of new Cubane Dervatives<\/li>\n<\/ul>\n<\/li>\n<li>13.55\u201314.20 Dr James Bull (Imperial College London)\n<ul>\n<li>Synthesis of N-Heterocycles as 3-D Fragments: Strategies for a Faster Escape from Flatland<\/li>\n<\/ul>\n<\/li>\n<li>14.20\u201314.45 Dr Jeff St Denis (Astex)\n<ul>\n<li>The Influence of Size and Shape in Fragment-Based Drug Discovery<\/li>\n<\/ul>\n<\/li>\n<li>14.45\u201315.10 Dr Rob Young (GSK)\n<ul>\n<li>Why Pharma needs tools to explore 3D space; the pitfalls of flatness (and fatness)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>15.10\u201315.45 Coffee\/posters<\/p>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"section\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p><strong>Session 3<\/strong>: Chaired by Prof. Peter O\u2019Brien (University of York)<\/p>\n<ul>\n<li>15.45\u201316.10 Dr Elaine O\u2019Reilly (University of Nottingham)\n<ul>\n<li>Biocatalytic strategies for chiral amine synthesis<\/li>\n<\/ul>\n<\/li>\n<li>16.10\u201317.10 Prof Erick Carreira (ETH Zurich)\n<ul>\n<li>Recent Developments in Strategies and Tactics Towards Complex Secondary Metabolites as enabling tools for the Study of Natural Products Biology<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>17.10 Drinks reception, then close.<\/p>\n<p>A meeting report may be downloaded: \u00a0<a href=\"http:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/DaM-3D-meeting-report-3-POB.docx\">DaM 3D meeting report 3-POB<\/a><\/p>\n<\/div>\n<p><a href=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"3661\" data-permalink=\"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/3d_space\/sponsors-2\/\" data-orig-file=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?fit=1255%2C260&amp;ssl=1\" data-orig-size=\"1255,260\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1523360582&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Sponsors\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?fit=300%2C62&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?fit=1024%2C212&amp;ssl=1\" class=\"alignnone size-full wp-image-3661\" src=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?resize=1140%2C236\" alt=\"\" width=\"1140\" height=\"236\" srcset=\"https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?w=1255&amp;ssl=1 1255w, https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?resize=300%2C62&amp;ssl=1 300w, https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?resize=768%2C159&amp;ssl=1 768w, https:\/\/i0.wp.com\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-content\/blogs.dir\/sites\/50\/2017\/07\/Sponsors.jpg?resize=1024%2C212&amp;ssl=1 1024w\" sizes=\"auto, (max-width: 1140px) 100vw, 1140px\" \/><\/a><\/p>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dial-a-Molecule Theme 3 Synthesis College Synthetic Tools for the Exploration of 3D Pharmaceutical Space &nbsp; When:\u00a0Friday 17th November 2017 Where:\u00a0University of York Overview: This free-to-attend meeting brought together 80 researchers at all career stages, from industry and academia, to learn about and discuss recent developments in the synthesis, analysis and biological evaluation of 3D molecules &hellip; <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/3d_space\/\">Continue reading<\/a><\/p>\n","protected":false},"author":1404,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-3530","page","type-page","status-publish","hentry","nodate","item-wrap"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P6CjJ1-UW","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/pages\/3530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/users\/1404"}],"replies":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/comments?post=3530"}],"version-history":[{"count":9,"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/pages\/3530\/revisions"}],"predecessor-version":[{"id":3677,"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/pages\/3530\/revisions\/3677"}],"wp:attachment":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/dial-a-molecule\/wp-json\/wp\/v2\/media?parent=3530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}