{"id":1164,"date":"2024-11-12T12:40:59","date_gmt":"2024-11-12T12:40:59","guid":{"rendered":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/?p=1164"},"modified":"2024-11-14T12:20:41","modified_gmt":"2024-11-14T12:20:41","slug":"chief-study-cochlear-implants-and-inner-ear-inflammation","status":"publish","type":"post","link":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/2024\/11\/12\/chief-study-cochlear-implants-and-inner-ear-inflammation\/","title":{"rendered":"CHIEF study: Cochlear Implants and Inner Ear Inflammation"},"content":{"rendered":"\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-cover alignwide is-light has-background-color has-text-color has-link-color has-crete-round-font-family wp-elements-87e8402fbe04ff0907a0470951d23037\" style=\"min-height:350px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\" style=\"background-color:#91aba7\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"2048\" height=\"2560\" class=\"wp-block-cover__image-background wp-image-1048\" alt=\"\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-scaled.jpg 2048w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-240x300.jpg 240w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-819x1024.jpg 819w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-768x960.jpg 768w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-1229x1536.jpg 1229w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/cayetano-gil-GIVExt4BQSY-unsplash-1638x2048.jpg 1638w\" sizes=\"auto, (max-width: 2048px) 100vw, 2048px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<h2 class=\"wp-block-heading has-text-align-left has-white-color has-text-color has-link-color wp-elements-3f38a940bdcb6c4502811b4fc055a3b3\" style=\"font-size:60px\">CHIEF study: Cochlear Implants and Inner Ear Inflammation<\/h2>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center\"><em>The CHIEF study is done in collaboration with the Manchester Paediatric and Adolescent Cochlear Implant Programme team.<\/em><\/p>\n\n\n\n<div class=\"wp-block-group is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-23441af8 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"240\" height=\"76\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/image.png\" alt=\"\" class=\"wp-image-795\" style=\"width:250px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1057\" height=\"631\" src=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold.png\" alt=\"\" class=\"wp-image-793\" style=\"width:250px\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold.png 1057w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold-300x179.png 300w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold-1024x611.png 1024w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold-768x458.png 768w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold-452x270.png 452w\" sizes=\"auto, (max-width: 1057px) 100vw, 1057px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"379\" height=\"119\" src=\"http:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/UoS-logo-e1731415159791.png\" alt=\"\" class=\"wp-image-794\" style=\"width:300px\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/UoS-logo-e1731415159791.png 379w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/UoS-logo-e1731415159791-300x94.png 300w\" sizes=\"auto, (max-width: 379px) 100vw, 379px\" \/><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">About the CHIEF study<\/h2>\n\n\n\n<p>We are investigating how well people hear with their cochlear implant.<\/p>\n\n\n\n<p>Many people benefit greatly from their implant but there are a few people do not have a positive experience. Why this happens is unknown.<\/p>\n\n\n\n<p>We are investigating how cells inside the cochlea (inner ear) respond to the implant. Other research has shown that how cells respond to the implant (the cellular response) differs between people. What causes the difference is not clear. We do not know if or how this links with how well someone does with their cochlear implant. Each immune system is exposed to different things across time. We think this might affect the immune state of tissues in the body, including in the ear.<\/p>\n\n\n\n<p>In this study, we want to investigate the inflammatory state of the middle and inner ear to see if this affects how well a person does with their cochlear implant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Study aim<\/h2>\n\n\n\n<p>To identify differences in inflammation in the ear between children and young people at the time they undergo cochlear implantation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Who is eligible to take part?<\/h2>\n\n\n\n<p>We are inviting children and young people, 16 or younger and eligible for a cochlear implant at Manchester University NHS Foundation Trust.<\/p>\n\n\n\n<p>Information about the study will be given to children and young people, as well as parents and guardians, during the information session that is part of the cochlear implant assessment pathway. The implanting surgeon will talk through the study in more detail and discus the participant information sheet. This will be a good opportunity to ask any questions you have. If you and your parent(s)\/guardian(s) are happy for you to take part &#8211; you will provide consent and be recruited into the study.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Study design<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"719\" height=\"1019\" src=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-1.png\" alt=\"\" class=\"wp-image-1172\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-1.png 719w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-1-212x300.png 212w\" sizes=\"auto, (max-width: 719px) 100vw, 719px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"722\" height=\"1006\" src=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-2.png\" alt=\"\" class=\"wp-image-1173\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-2.png 722w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-2-215x300.png 215w\" sizes=\"auto, (max-width: 722px) 100vw, 722px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-3.png\" alt=\"\" class=\"wp-image-1174\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"719\" height=\"1004\" src=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-4.png\" alt=\"\" class=\"wp-image-1175\" srcset=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-4.png 719w, https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/11\/Chief-4-215x300.png 215w\" sizes=\"auto, (max-width: 719px) 100vw, 719px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<p>If you have any questions about the study, please <a href=\"mailto:K.L.hough@soton.ac.uk\" data-type=\"mailto\" data-id=\"mailto:K.L.hough@soton.ac.uk\" target=\"_blank\" rel=\"noreferrer noopener\">contact Kate Hough<\/a>.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-buttons is-content-justification-right is-layout-flex wp-container-core-buttons-is-layout-d445cf74 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-font-size has-small-font-size\"><a class=\"wp-block-button__link has-primary-background-color has-background wp-element-button\" href=\"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/\">Return to our home page<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The CHIEF study is done in collaboration with the Manchester Paediatric and Adolescent Cochlear Implant Programme team. About the CHIEF study We are investigating how well people hear with their cochlear implant. Many people benefit greatly from their implant but there are a few people do not have a positive experience. Why this happens is [&hellip;]<\/p>\n","protected":false},"author":5645,"featured_media":793,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[8,7],"tags":[],"class_list":["post-1164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-current","category-research"],"jetpack_featured_media_url":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-content\/uploads\/sites\/455\/2024\/09\/CHIEF-Logo-bold.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/posts\/1164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/users\/5645"}],"replies":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/comments?post=1164"}],"version-history":[{"count":4,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/posts\/1164\/revisions"}],"predecessor-version":[{"id":1336,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/posts\/1164\/revisions\/1336"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/media\/793"}],"wp:attachment":[{"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/media?parent=1164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/categories?post=1164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/generic.wordpress.soton.ac.uk\/all-ears\/wp-json\/wp\/v2\/tags?post=1164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}